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What does the science say about the benefits of L-Lysine


You’ve probably heard that L-lysine can help boost your immune system. While this may be true, studies show that lysine, an essential amino acid, has more benefits than its immunomodulatory effects. Lysine plays an essential role in the production of carnitine, a nutrient responsible for converting fatty acids into energy and helping lower cholesterol. Moreover, lysine plays a role in the formation of collagen, which is important for bones and connective tissues including skin, tendons, and cartilage. We will talk about how lysine works, the benefits, and how this essential amino acid, is vital to human health.

What is L-Lysine?

L-Lysine is an essential amino acid (EAA) that plays many biological functions essential to human health. It is considered dibasic Amino acids along with amino acids such as arginine, cysteine ​​and ornithine due to the presence of a second basic group [R].

Lysine plays an important role in the formation of collagen, which is a structural protein, protein synthesis and the muscle building process, and the production of carnitine which is an amino acid complex composed of lysine and methionine, which helps transport fatty acid chains across cells that are transported for fat oxidation and energy conversion.

Lysine benefits

1. May Protect Against Herpes Simplex Virus (HSV)

Research suggests that taking l-lysine preventively may help protect against and prevent herpes simplex virus (HSV) outbreaks in the form of cold sores and genital herpes.

Cold sores and genital warts are symptoms of infection that appear on the lips and genitals in the form of fever blisters. Cold sores are caused by HSV-1 or herpes simplex virus-1. They appear during times of stress when your immune system is weakened.

Lysine has antiviral effects that increase the level of arginase, and inhibit the activity of arginine that promotes herpes simplex virus replication.[R].

A review found that doses of lysine greater than 3 grams per day may improve subjective symptoms for cold sore sufferers. [R]. Subjective symptoms can be pain, tingling, or discomfort. Although placebo effects can be powerful, more research is needed to determine whether lysine is in fact effective for treating herpes simplex virus.

2. May improve calcium absorption

Lysine is thought to increase calcium absorption and reduce the amount of calcium present in the urine. Certain amino acids, such as tryptophan, phenylalanine, and histidine are able to increase calcium absorption through calcium-sensing receptors (CASR). It was found that lysine has an obvious effect on calcium absorption.

A study published in the journal feed It was found that supplementing a low protein diet (0.7 g/kg) with a large amount of the dibasic amino acids lysine and Arginine It was able to increase calcium absorption and elimination more significantly than a diet containing mixed amino acids or the above three CASRs. The study found that adding 400mg of lysine to 3g of calcium chloride in both healthy and osteoporotic women increased calcium absorption and decreased the rate of excretion. [R].

3. Collagen is secreted for wound healing

Lysine has been found to be more active on specific wound sites to improve the healing and repair process. It plays an important role in the formation of collagen, a structural protein found in ligaments, skin, cartilage, and joints.

Lysine has the ability to trigger powerful anti-inflammatory and immune responses, and has been shown to help increase wound healing (both acute and chronic). [R].

A randomized controlled trial used a combination of lysine and hyaluronic acid (Lysine hyaluronate, Lysial) to evaluate its effects on skin ulcers over a 15-day period.

Fifty hospitalized patients with decubitus ulcers were divided into three groups according to the stage of the ulcer (stage 1: erythema and edema; stage 2: complete skin destruction; stage 3: subcutaneous tissue destruction) and randomized to receive Lys-HA or sodium hyaluronate (u). ).

Ulcer reduction was greater in all lysine-hyaluronate groups than in the SH groups. In stage I patients, a 90% and 70% reduction in lesion size was observed in the groups assigned to Lys-HA and SH, respectively (p < 0.05). In stage II patients, a reduction in lesion size of 70% and 40% was observed in the Lys-HA and SH groups, respectively (P < 0.02). In stage III patients, a reduction in lesion size of 71% and 29% was observed in the Lys-HA and SH groups. [R].

Lysine Benefits:

Lysine is involved in many biological functions that are critical and vital to human health. As an essential amino acid, it must be obtained from food or supplements, as the human body cannot produce it on its own. Lysine is important for the growth and creation of proteins and collagen and in the formation of carnitine, a nutrient responsible for converting fatty acids into energy and helping lower cholesterol. Adding a high-quality essential amino acid (EAA) supplement to your nutrition plan is an easy way to improve performance and overall health.



Looking for a supplement with a healthy dose of L-Lysine

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Walter Henchman

Walter Henchman is the founder and CEO of Swolverine. He is a NESTA and ACE certified instructor and holds a master’s degree in Business, Finance and Economics.


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